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CRISPR Diagnostics: Advances toward the Point of Care.
Daniel J Brogan, Omar S Akbari
Biochemistry · 2023-Dec-19 · PMID 35325535 · DOI 10.1021/acs.biochem.2c00051Abstract
CRISPR diagnostics have recently emerged as powerful diagnostic tools for the rapid detection of infections. The ultimate goal is to develop these diagnostics for the point of care, where patients quickly receive and easily interpret results. Although they are in their infancy, the COVID-19 pandemic has accelerated innovation of CRISPR diagnostics and led to an explosion of improvements to these systems. Challenges that have impeded the implementation at the point of care have been addressed, and CRISPR diagnostics have been dramatically simplified. Here we outline recent developments and advancements in CRISPR diagnostics that have pushed these technologies to the point of care.
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- Conflict statement
- The authors declare no competing financial interest.