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A gene drive is a gene drive: the debate over lumping or splitting definitions.

Stephanie L James, David A O'Brochta, Filippo Randazzo, Omar S Akbari

Nature communications · 2023-Mar-29 · PMID 36991021 · DOI 10.1038/s41467-023-37483-z

Abstract

We address a controversy over use of the term “gene drive” to include both natural and synthetic genetic elements that promote their own transmission within a population, arguing that this broad definition is both practical and has advantages for risk analysis.

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laboratory
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published
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Conflict statement
O.S.A is a founder of Agragene, Inc. and Synvect, Inc. with equity interest. The terms of this arrangement have been reviewed and approved by the University of California, San Diego in accordance with its conflict of interest policies. All other authors declare no competing interests.

Topics and methods

Gene drivesGene drive

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